Hatice Gülen

Profesör Doktor

Mühendislik ve Doğa Bilimleri Fakültesi / Genetik ve Biyomühendislik Bölümü

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  • Academic Background

     

    • 2000, PhD., Horticulture, Cukurova University; Plant & Soil Sci., West Virginia Univ., USA
    • 1992, MS., Horticulture, Cukurova University
    • 1988, BS., Horticulture, Cukurova University

     

     

    Academic Appointments

     

    • 2016-present, Full Professor, Istanbul Bilgi University, Dept. of Genetics and Bioengineering
    • 2011-2016, Full Professor, Horticulture Dept., Uludag University
    • 2013-2016, Full Professor, Dept. of Molecular Biology and Genetics (Graduate Program), Uludag University
    • 2005-2011, Associate Professor, Horticulture Dept., Uludag University
    • 2000-2005, Postdoctoral Fellow, Horticulture Dept., Uludag University
    • 1998-1999, Visiting Scholar, Div. of Plant & Soil Sci., West Virginia Univ., USA
    • 1996-2000, Research Assistant, Horticulture Dept., Cukurova University
    • 1989-1994, R&D Department of Commercial Plant Tissue Culture Lab., Basagene Ltd. Co., Adana

     

     


    Scholarships and Courses

     

    • June-Sept. 2009, Visiting Scientist, Div. of Plant & Soil Sci. (Plant Genetics Lab.) West Virginia Univ., USA
    • May-July 2006, MASHAW Scholarship, (Biotechnology and Bioinformatics in Agriculture- Plants and microorganisms) Fac. of Agr. Food and Environ. Quality Sci., The Hebrew Univ. of Jerusalem, Israel
    • December 1998-July 1999, West Virginia Univ. Foundation Grant (USA),(Due to a part of Ph.D work at West Virginia Univ., Div. of Plant & Soil Sci. USA)
    • May-November 1998, TUBITAK NATO A-2 Scholarship,(Due to a part of Ph.D work at West Virginia University, Division of Plant & Soil Sci., USA)
    • June-July 1995, CHIEAM Scholarship (Greece), Plant Biotechnology and Application, MAICH, Crete, Greece
    • Aug.-Sept.1993, Production of In Vitro Seed Potato, Cornell Univ., Plant Pathology Dept., USA

     

     

     

    Research Interests

     

    • Biotechnology
    • Plant molecular biology (enzyme and protein metabolism)
    • Plant physiology (growth & development; PGR)
    • Plant stress physiology

     

     

    Teaching

     

    • BIOE 435 Concept and Issues in Biotechnology
    • BIOE 438 Green Biotechnology
    • BIOE 348 Physiology
    • BIOE 325 Cell and Tissue Culture

     

     

    Projects

     

    • 2016-, Development of new cultivars with high frost tolerance and elucidating candidate genes responsible for protein and carbohydrate metabolisms in frost stress of olive. TUBITAK (Project # TOVAG-215O797), Project Coordinator
    • 2012-2016, Identification of differentially expressed genes and proteins in strawberry plants under heat stress. Uludag University, Research Foundation (Project # 2012/50), Project Coordinator
    • 2012-2016, Identification of Ficus carica cv. Bursa Siyahi using SSR molecular markers. Uludag University, Research Foundation (Project # KUAP(Z) 2012/50), Project Coordinator
    • 2011-2016, Mapping nuclear genes controlling male sterility in carrot using AFLP markers. TUBITAK (Project No: TOVAG-111 O 119), Researcher
    • 2013-, Effects of high temperature stress on dehydrin proteins and phospholipid metabolism in strawberry plants. Uludag University, Research Foundation (Project # 2013/14), Researcher
    • 2010-2014, Effects of glycine betain and choline applications on phospholipid metabolism of olive plants under low temperature stress. Uludag University, Research Foundation (Project # UAP(Z)-2010/47), Researcher
    • 2008-2011, Effects of high temperature stress on antioxidant, carbohydrate and protein metabolism of strawberry plants. TUBITAK (Project # TOVAG-108O061), Project Coordinator
    • 2006-2009, DNA fingerprinting of some berry cultivars by AFLP and SSR molecular markers. Uludag University, Research Foundation (Project # Z-2006/57), Researcher
    • 2006-2009, Identification of some local and introduced cherry cultivars by AFLP and SSR molecular markers. Uludag University, Research Foundation (Project # Z-2006/36), Project Coordinator)
    • 2005-2008, Determination of DNA profiles of some important olive varieties and hybrids and the development of olive genetic map using molecular markers. TUBITAK (Project # TOVAG-105 O 071), Researcher
    • 2002-2007, Molecular biological characterization of cold hardiness in olive plants (Olea europaea L.). DPT (Project # 2002/1), Researcher
    • 2000-2002, Prediction of graft compatibility of some quince rootstocks with some pear scions using peroxidase isoenzyme analysis. Uludag University, Research Foundation (Project # 2001/57), Project Coordinator
    • 1996, In vivo and in vitro propagation of globe artichoke. Cukurova University, Faculty of Agriculture Foundation (Project # BAP BB-96/11), Researcher

     

     

    Selected Publications

     

    1. Ipek, A., Yılmaz, K., Sıkıcı, P., Aktepe Tangu, N., Oz, A. T.,Bayraktar, M., Ipek, M. and Gulen, H. 2016. SNP discovery by GBS in olive and the construction of a high-density genetic linkage map. Biochem. Genet., DOI 10.1007/s10528-016-9721-5.
    2. Sahan Y., Cansev A. and Gulen, H. 2013. Effect of processing techniques on antioxidative enzyme activities, antioxidant capacity, phenolic compounds, and fatty acids of table olives. Food Sci. Biotech., 22: 613-620.
    3. Kesici M., Gulen, H., Ergin S., Turhan E., Ipek A. and Koksal N. 2013. Heat-stress tolerance of some strawberry (Fragaria x ananassa) cultivars. Not. Bot. Horti. Agrobo. 41(1): 238-243.
    4. Ipek A., Barut E., Gulen, H. and Ipek M. 2012. Assessment of inter-and intra-cultivar variations in olive using SSR markers. Sci. Agric., 69(5): 327-335.
    5. Cansev, A., Gulen, H., Celik, G. and Eris, A. 2012. Alterations in total phenolic content and antioxidant capacity in response to low temperatures in olive (Olea europaea L. Gemlik). Plant Archives, 12(1): 489-494.
    6. Ergin, S., Kesici, M. and Gulen, H. 2012. Changes in H2O2 and peroxidase activities in strawberry plants under heat stress. J. Agric.Fac.HR.U, 16 (1): 25-35.
    7. Koksal, N., Gulen, H. and Eris, A. 2011. Dormancy in tulip (Tulipa gesneriana L.) bulbs and freesia (Freesia refracta Klatt.) corms: Changes in soluble proteins and APX activity. J. Food Agr. Environ., 9(2): 535-539.
    8. Cansev, A.,Gulen, H. and Eris, A. 2011. The activities of catalase and ascorbate peroxidase in olive (Olea europaea L. Gemlik ) under low temperature stress. Hort. Environ. Biotech. 52(2): 113-120.
    9. Zaimoglu, Z., Koksal, N., Basci, N., Kesici, M., Gulen, H. and Budak, F. 2011. Antioxidative enzyme activities in Brassica juncea L. and Brassica oleracea L. plants under chromium stress. J. Food Agr. Environ. 9(1): 676-679.
    10. Ipek, A., Gulen, H. , Akcay, M.E., Ipek, M., Ergin, S. and Eris, A. 2011. Determination of self-incompatibility groups of sweet cherry genotypes from Turkey. Gen. Mol. Res. 10(1): 253-260.
    11. Oz, A. T., Gulen, H. and Eris, A. 2010. The effect of harvest maturity stage on ACC synthase activity and total proteins profile in kiwifruits during normal and controlled atmosphere storages. Int. J. Agr. Biol. 12: 828-832.
    12. Gulen, H. , Ipek A., Ergin S., Akcay M. E. and Eris A. 2010. Assessment of genetic relationship among 29 introduced and 49 local sweet cherry accessions in Turkey using AFLP and SSR markers. J. Hort. Sci. Biotech. 85(5): 427-431.
    13. Ipek A., Barut E., Gulen, H. and Ipek M. 2010. Genetic diversity among some currants (Ribes spp.) cultivars as assessed by AFLP markers. Pak. J. Bot. 42: 1009-1012.
    14. Ipek A., Barut E., Gulen, H. , Tangu N.A. and Ipek M. 2009. SSR analysis demonstrates that olive production in the southern Marmara region in Turkey uses a single genotype. Gen. Mol. Res. 8(4): 1264-1272.
    15. Ipek A., Barut E., Gulen, H. and Ipek M. 2009. Genetic diversity among some blackberry cultivars and their relationship with Boysenberry assessed by AFLP markers. Afric. J. Biotech. 8: 4830-4834.
    16. Ipek, A., Gulen, H. , Akcay, M.E., Ipek, M., Ergin, S. and Eris, A. 2011. Determination of self-incompatibility groups of sweet cherry genotypes from Turkey. Gen. Mol. Res. 10(1): 253-260.
    17. Barut E., Ipek A. and Gulen, H. 2009. Distribution of olive (Olea europaea L.) genotypes in the southern Marmara region of Turkey. Pak. J. Bot. 41: 1077-1080.
    18. Gulen, H., Cansev A. and Eris A. 2009. Cold-hardiness of olive (Olea europaea L.) cultivars in cold-acclimated and non-acclimated stages: Seasonal alteration of soluble sugars and phospholipids. J. Agr. Sci. 147: 459-467.
    19. Gulen, H., Cansev A. and Eris A. 2009. Cold-hardiness of olive (Olea europaea L.) cultivars in cold-acclimated and non-acclimated stages: Seasonal alteration of antioxidative enzymes and dehydrin-like proteins. J. Agr. Sci . 147: 51-61.
    20. Gulen, H., Cetinkaya C., Kadioglu M., Kesici M., Cansev A. and Eris A. 2008. Peroxidase activity and lipid peroxidation in strawberry (Fragaria X ananassa) plants under low temperature. J. Biol. Environ. Sci. 2(6): 95-100.
    21. Turhan, E., Gulen, H. and Eris, A. 2008. The activity of antioxidative enzymes in three strawberry cultivars related to salt stress tolerance. Acta Physiol. Plant. 30:201-208.
    22. Eris, A., Gulen, H., Barut, E. and Cansev, A. 2007. Annual patterns of total soluble sugars and proteins related to cold-hardiness in olive (Olea europaea L. Gemlik). J. Hort. Sci. Biotech. 82: 597-604.
    23. Gulen, H., Celik, M., Polat, M. and Eris, A. 2005. Cambial isoperoxidases related to graft compatibility in pear-quince graft cominations. T. J. Agr. Forest. 29 (1): 83-89.
    24. Gulen, H., Kuden, A., Postman, J. and Arora, R. 2005. Total protein and SDS-PAGE in pear scions grafted on quince A and pear seedling rootstocks. T. J. Agr. Forest. 29 (1): 91-96.
    25. Gulen, H., Erbil, Y. and Eris, A. 2004. Improved rooting of Gisela-5 softwood cuttings following banding and application of IBA. HortScience 39(6): 1403-1405.
    26. Gulen, H. and Eris, A. 2004. Effect of heat stress on peroxidase activity and protein content in strawberry plants. Plant Sci. 166(3): 739-744.
    27. Gulen, H. and Eris, A. 2003. Some physiological changes in strawberry (Fragaria x ananassa cv. Camarosa) plants under heat stress. J. Hort. Sci. Biotech. 78 (6): 894-898.
    28. Gulen, H., Arora, R., Kuden, A., Krebs, S.L. and Postman, J. 2002. Peroxidase isozyme profiles in compatible and incompatible pear/quince graft combinations. J. Amer. Soc. Hort. Sci. 127(2):152-157.

     

     

     

    Presentations (Symposium & Congress)

    1. Gulen, H. and Zaimoglu, Z. 2014. Green biotechnology: Opportunities for sustainable development under climatic change. 25th Scientific-Experts Congress on Agriculture and Food Industry, 25-27 Sept. 2014, Izmir, Abstract Book, p. 127.
    2. Ergin, S., Kesici, M. and Gulen, H. 2014. Low temperature tolerance of leaf tissues in cold-acclimated strawberry plants. Proceedings of 25th Scientific-Experts Congress on Agriculture and Food Industry, 25-27 Sept. 2014, Izmir, 205-208.
    3. Kesici Zengin, M., Ergin, S., Cansev, A., and Gulen, H. 2013. Choline chloride as a growth stimulator in strawberry plants. Proceedings of 24th International Scientific-Experts Congress of Agriculture and Food Industry, 25-28 Sept. 2013, Sarajevo, 487-489.
    4. Zaimoglu, Z., Gulen, H., Bostan Budak, D., Ergin, S. and Kesici, M. 2012. The assassment of the behavior of nanoparticles in environmental systems for sustainable development. 15th. European Congress on Biotechnology, 23-26 Sept. 2012, Istanbul, Turkey, Abstract Book, p. 220.
    5. Ergin, S., Gulen, H., Turhan, E., Ipek, A., Koksal, N. and Kesici, M. 2012. Proteins in strawberry plants (Fragaria x ananassa Duch.) under heat stress. 15th. European Congress on Biotechnology, 23-26 Sept. 2012, Istanbul, Turkey, Abstract Book, p. 22.
    6. Kesici, M., Cansev, A., Ergin, S. and Gulen, H. 2012. Protein and peroxidase activity in strawberry plants under the combined effects of drought, low and high temperature. 15th. European Congress on Biotechnology, 23-26 Sept. 2012, Istanbul, Turkey, Abstract Book, p. 185.
    7. Cansev, A., Kesici, M., Ergin, S. and Gulen, H. 2012. Effects of high temperature stress on total phenolic content and antioxidant capacity in strawberry plants. 15th. European Congress on Biotechnology, 23-26 Sept. 2012, Istanbul, Turkey, Abstract Book, p. 120.
    8. Cansev, A., Gulen, H., İpek M. and Barut, E. 2012. Determination of non-phytotoxic doses of glycine betaine and choline in Olea europaea L. 15th. European Congress on Biotechnology, 23-26 Sept. 2012, Istanbul, Turkey, Abstract Book, p. 175.
    9. Gulen, H., Ipek, A. and Turhan, E. 2012. Effects of antioxidant enzymes on heat stress tolerance of pepper (Capsicum annum L.) seedlings. International Symposium on Biotechnology and Other Omics in Vegetable Science. April 29- May 2, Antalya, Turkey, Abstract Book, p.47.
    10. Cansev, A., Gulen, H., Celik, G. and Eris, A. 2010. Changes in total phenolic content and antioxidant capacity in response to low temperatures in olive (Olea europaea L. Gemlik). Workshop on Antioxidant Measurement Assay Methods, April, 21 2010, Istanbul, Turkey, Abstract Book, p. 29.
    11. Turhan, E., Gulen, H., Ipek, A. and Eris, A. 2009. Antioxidative enzyme activities in onion (Allium cepa L.) genotypes. Proceedings of International Conference On Evironment: Survival and Sustainability, 19-24 February 2007, Near East University, Nicosia, Northern Cyprus. Vol. 2: 459-466.
    12. Ipek, A., Turhan, E., Koksal, N., Gulen, H. and Eris, A. 2009. Carbohydrate metabolism in pepper (Capsicum annum L.) seedlings under high temperature stress. Proceedings of International Conference On Evironment: Survival and Sustainability, 19-24 February 2007, Near East University, Nicosia, Northern Cyprus. Vol.2: 753-760.
    13. Gulen, H., Turhan E., Koksal N., Cansev A., Zaimoglu Z. and Eris A. 2009. Physiological and molecular effects of high temperature on plant growth and development. Proceeding of 1st. International Congress on Global Climate Changes and Agriculture, May 28-30 2009, Tekirdag, Turkey, 247-253.
    14. Gulen, H., Koksal N., Cansev A., Demir S., Zaimoglu Z. and Eris A. 2009. Antioxidative enzyme activities in strawberry plants under cadmium stress. 1st. International Workshop on Application of Redox Technologies in the Environment, Sept. 14-15, 2009, Istanbul, Turkey, Abstract Book, 181-183.
    15. Zaimoglu Z., Budak F. and Gulen, H. 2009. New energy source- biomass algea. Proceeding of 1st. International Congress on Global Climate Changes and Agriculture, May 28-30 2009, Tekirdag, Turkey, p. 246.
    16. Gulen, H., Ipek, A., Burak, M. and Eris A. 2008. Assesment of genetic diversity and relationship among some sweet cherry cultivars using AFLPTM markers. 5th International Cherry Symposium, 06-10 June 2005, Bursa-Turkey, Acta Hort. 795: 127-130.
    17. Cansev, A., Gulen, H., Ipek, A. and Eris, A. 2006. Seasonal changes in various enzyme activities in olive (Olea europaea L.) genotypes. Plant Biology 2006, Boston, Massachusetts, August 05-09, 2006; PO9004, 140.
    18. Gulen, H., Kuden, A., Krebs, S.L., Postman, J. and Arora, R. 2001. Electrophoretic detection of pear/quince graft incompatibility using peroxidase and total protein analysis. Proceeding of the 1st. Eurasian Congress on Molecular Biotechnology, Vol. 1, 142-145.
    19. Gulen, H., Kuden, A., Lim, C.C., Krebs, S.L., Postman, J. and Arora, R. 1999. Isoperoxidase and protein patterns in compatible and incompatible pear/quince graft combinations. HortScience, Vol.34(3):483.
    20. Gulen, H. and Kuden, A. 1998. Micropropagation of some vegetative rootstocks of sweet and sour cherry by meristem culture. Progress in Botanical Research, Kluwer Academic Publishers, 501-504.

     

    Patents

    TPI (Turkish Patent Institute) Patents

    • Using of Uridine in plant growth and development
      TR 2013 02102 B, 2015.
      A.Cansev H. Gulen, S. Ergin, M. Kesici, M. Cansev
    • Using of Cytidine in plant growth and development
      TR 2013 02103 B, 2015. A. Cansev
      H. Gulen, S. Ergin, M. Kesici, M. Cansev

     

    TPI, European Patent Office (EPO), United States Patent and Trademark Office (USPTO)

    • Use of Pyrimidines in Stimulation of Plant Growth and Development and Enhancement of Stress Tolerance (under investigation)
      TPE # TR2014/000051
      EPO # 14722798.7
      A. Cansev, H. Gulen, S. Ergin, M. Kesici, M. Cansev, A. Kumral
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  • Ofis: 0212 311 77 51

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  • santralistanbul Kampüsü,
    EN-1 107

    Adres: Eski Silahtarağa Elektrik Santralı Kazım Karabekir Cad. No: 2/13 34060 Eyüp İstanbul

Hatice Gülen