1. Ali Deniz Dalgıç
Faculty Member, PhD

Ali Deniz Dalgıç

deniz.dalgic@bilgi.edu.tr

+90 212 311 7936

https://scholar.google.com/citations?user=Kc7xjDQAAAAJ&hl=tr&oi=ao

Santralistanbul / EN1-108

Academic Experience

2021-Present, Assistant Professor, Department of Genetics and Bioengineering, Istanbul Bilgi University, Turkey.

2012-2020, Research and Teaching Assistant, Department of Engineering Sciences, Middle East Technical University, Turkey. 

Education

PhD, 2020            Department of Engineering Sciences, Biomechanics Graduate Program, Middle East Technical University, Ankara, Turkey

MSc, 2014           Department of Engineering Sciences, Biomechanics Graduate Program, Middle East Technical University, Ankara, Turkey

BSc, 2011            Department of Biological Sciences, Middle East Technical University, Ankara, Turkey

Courses

BIOE 334 BIOMATERIALS 

BIOE 221 INDUSTRIAL MICROBIOLOGY 

BIOE 323 GENETIC ENGINEERING I

BIOE 324 GENETIC ENGINEERING II

Areas of Interest

Tissue Engineering and Regenerative Medicine

             Development of scaffold systems for tissue engineering applications

Controlled Drug Delivery Systems

             Targeted drug delivery, Micro-Nanoparticles for drug delivery

Other Information

Projects

  • TÜBİTAK 1001, Project: 215M893, 01.05.2016-13.02.2019 “An Investigation of the Usability of Diatom Silica Skeleton-Reinforced Polyhydroxybutyrate-cohydroxivalate / Pullulan Three Dimensional Tissue Scaffolds in Bone Tissue Engineering” Scholar
  •             METU, Department of Engineering Sciences, DAP-08-11-2012-016, 01.01.2012-31.12.2013 “Investigation of the In vitro Efficacy of New Liposomal System Containing Anticancer Drugs and Anti-CD20 Antibody in the Treatment of Leukemia and Lymphoma Diseases”, Researcher
  • METU, Department of Engineering Sciences, BAP-07-02-2014-007-610, 01.01.2014-31.12.2016, Graduate school of natural and applied sciences, MSc Thesis Project. Researcher
  • METU, Department of Engineering Sciences, GAP-310-2022-10875, 17.01.2022- 17.01.2023, “Menadione (Vitamin K3) and Doxorubicin dual loaded liposomes for enhanced anticancer effect.” Researcher
  • Istanbul Bilgi University, Dept. of Genetics and Bioengineering, 01.04.2022-01.04.2023. "Development of Scaffold/Liposome System for Local Thalidomide Release for Post-Surgery Treatment After Breast Cancer Tumor Removal (Project No: 2021.02.005)" Coordinator

Publications

  1. Dalgic, A. D., Atila, D., Tezcaner, A., Gürses, S., & Keskin, D. (2023). Diatom Silica Frustules-Doped Fibers for Controlled Release of Melatonin for Bone Regeneration. European Polymer Journal, 111858.
  2. Motameni, A., Alshemary, A. Z., Dalgic, A. D., Keskin, D., & Evis, Z. (2022). Graphene oxide reinforced doped dicalcium phosphate bone cements for bone tissue regenerations. Journal of the Australian Ceramic Society, 58(5), 1633-1647.
  3. Alshemary, A. Z., Hussain, R., Dalgic, A. D., & Evis, Z. (2022). Bactericidal and in vitro osteogenic activity of nano sized cobalt-doped silicate hydroxyapatite. Ceramics International, 48(19), 28231-28239.
  4. Dalgic, A. D., Koman, E., Karatas, A., Tezcaner, A., & Keskin, D. (2022). Natural origin bilayer pullulan-PHBV scaffold for wound healing applications. Materials Science and Engineering: C, 112554.
  5. Erener, T., Ceritoğlu, K. U., Aktekin, C. N., Dalgic, A. D., Keskin, D., Geneci, F., Ocak, M., Bilecenoğlu, B., Hücümenoğlu, S., Çaydere, M., Şeneş, M. & Sezgin, Ö. (2021). Investigation of The Effect of Ghrelin on Bone Fracture Healing in Rats. Clinical and Experimental Pharmacology and Physiology, 48 (10), 1382-1390.
  6. Motemeni, A., Alshemary, A. Z., Dalgic, A. D., Keskin, D., & Evis, Z. (2021). Lanthanum doped dicalcium phosphate bone cements for potential use as filler for bone defects. Materials Today Communications, 26, 101774.
  7. Guner, M. B., Dalgic, A. D., Tezcaner, A., Yilanci, S., & Keskin, D. (2020). Dual phase scaffold produced by rotary jet spinning and electrospinning for tendon tissue engineering. Biomedical Materials, 15(6), 065014.
  8. Motemeni, A., Dalgic, A. D., Alshemary, A. Z., Keskin, D., & Evis, Z. (2020). Structural and Biological Analysis of Mesoporous Lanthanum Doped βTCP For Potential Use as Bone Graft Material. Materials Today Communications, 23, 101151.
  9. Alissa Alam, H., Dalgic, A. D., Tezcaner, A., Ozen, C., & Keskin, D. (2020). A comparative study of monoaxial and coaxial PCL/gelatin/Poloxamer 188 scaffolds for bone tissue engineering. International Journal of Polymeric Materials and Polymeric Biomaterials, 69(6), 339-350.
  10. Alshemary, A. Z., Pazarçeviren, E. A., Dalgic, A. D., Tezcaner, A., Keskin, D., & Evis, Z. (2019). Nanocrystalline Zn2+ and SO42− binary doped fluorohydroxyapatite: A novel biomaterial with enhanced osteoconductive and osteoinconductive properties. Materials Science and Engineering: C, 104, 109884.
  11. Dalgic, A. D., Atila, D., Karatas, A., Tezcaner, A., & Keskin, D. (2019). Diatom shell incorporated PHBV/PCL-pullulan co-electrospun scaffolds for bone tissue engineering. Materials Science and Engineering: C, 100, 735-746.
  12. Caliskan, Y., Dalgic, A. D., Gerekci, S., Gulec, E. A., Tezcaner, A., Can, O., Keskin, D. (2019). A new therapeutic combination for osteosarcoma: Gemcitabine and Clofazimine co-loaded liposomal formulation. International Journal of Pharmaceutics, 557, 97–104.
  13. Dalgic, A. D., Alshemary, A. Z., Tezcaner, A., Keskin, D., & Evis, Z. (2018). Silicate-doped nano-hydroxyapatite/graphene oxide composite reinforced fibrous scaffolds for bone tissue engineering. Journal of Biomaterials Applications, 32(10), 1392-1405.
  14. Gurturk, Z., Tezcaner, A., Dalgic, A. D., Korkmaz, S., & Keskin, D. (2017). Maltodextrin modified liposomes for drug delivery through the blood–brain barrier. MedChemComm, 8(6), 1337-1345.
  15. Dalgic, A. D., Tezcaner, A., Elci, P., Sarper, M., Arpaci, F., Avcu, F., & Keskin, D. (2016). Improvement of a liposomal formulation with a native molecule: calcitriol. RSC Advances, 6(83), 80158-80167.

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