Faculty Member, PhD
Özlem Ulucan Açan
Education
- PhD, 2015. Center for Bioinformatics, Saarland University, Saarbruecken, Germany.
- MSs, 2009. Computational Sciences and Engineering, Koc University, Istanbul, Turkey.
- BSc, 2007. Molecular Biology and Genetics, Istanbul University, Istanbul, Turkey.
Courses
- BIOE 341 Bioinformatics
- ENGR 411 Statistical Learning
- ENGR 240 Probability and Statistics for Engineers and Scientists
- BIOE 340 Modeling and Simulation in Bioengineering
- BIOE 348 Physiology
Areas of Interest
- Biomolecular Interactions
- Computer-aided Drug Design
- Functional Genomics
- Statistical Leaning and Data Analysis
Rewards and Achievements
- Socrates/Erasmus Program Scholarship, 2006.
- TUBİTAK National Scholarship Program for Graduate Students, 2007-2009.
- 09.2007 - 09.2009 Koc University Ful Scholarship, 2007-2009.
Other Information
Publications
- Shanak, S., Ulucan, O. and Helms V., Methylation-targeted specificity of the DNA binding proteins R.DpnI and MeCP2 studied by molecular dynamics simulations, J. Mol. Model, 2017, 23, 152.
- Ulucan, O., Helms V., How hydrophilic proteins form nonspecific complexes, J. Phys. Chem. B, 2015, 119 (33), 10524–10530 [EF: 3.177.
- Hochscherf, J., Lindenblatt, D., Steinkrüger, M., Yoo, E., Ulucan, Ö., Herzig, S., Issinger, O.-G., Helms, V., Götz, C., Neundorf, I., Niefind, K., Pietsch, M., Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2α/CK2β interaction, Analytical Biochemistry, 2014, 468, 4-14.
- Ulucan O, Jaitly T, Helms V., Energetics of Hydrophilic Protein-Protein Association and the Role of Water, JCTC, 2014, 10 (8), 3512–3524.
- Tretter T, Pereira FP, Ulucan O, Helms V, Alan S, Kalies KU, Romisch K., ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop7, BMC Cell Biology, 2013, 14, 56.
- Ulucan O, Eyrisch S, and Helms V., Druggability of Dynamic Protein-protein Interfaces, Curr Farm Des, 2012, 18(30), 4599-4606.
- Walter P, Ulucan O, Metzger J, Helms V., Bioinformatics of Protein-Protein Interfaces and Small Molecule Effectors, Current Bioinformatics, 2012, 7(2), 159-172.
- Schäuble N, Lang S, Jung M, Cappel S, Shorr S, Ulucan Ö, Linxweiler J, Dudek J, Blum R, Helms V, Paton AW, Paton JC, Cavalié A, Zimmerman R., BiP-mediated closing of Sec61 channel limits Ca2+ leakage from ER. EMBO J, 2012, 31(15), 3282–3296.
- Ulucan O, Keskin O, Erman B., Gursoy A., A comparative Molecular Dynamics Study of Methylation State Specificity of JMJD2A, PLoS ONE, 2011, 6(9): e24664.