Department of Genetics and Bioengineering 10th Anniversary Year (2010-11 - 2020-21) Seminar Series - Building the roof of mouth: Role of TGFβ in craniofacial development
The role of TGFβ in craniofacial and palate development was well documented two decades ago, but how this cytokine signals to bring palatal was not studied till 2003, when we first documented (J Cell Biology, 2003) that during palatal seam disintegration by TGFβ3 involve complex signaling pathways to disintegrate palatal seam. Subsequently, our lab has been contributing to identify downstream signaling cross talks, kinetics of interactions during palatal seam disintegration. In this talk, we will discuss few new findings of where we mapped a holistic gene expression and its relevant pathways in mutant mice. Moreover, we will briefly discuss our new project where we study the gene expression in periodontitis and how simvastatin (a commonly used cholesterol lowering drug) can repair/regenerate periodontal diseases.
Date: 30 March 2021, Tuesday
Ali Nawshad, Ph.D., Medical Center, University of Nebraska–Lincoln
Prof. Dr. Hatice Gülen, Faculty of Engineering and Natural Sciences, İstanbul Bilgi Üniversity
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